Page tree

Versions Compared

Key

  • This line was added.
  • This line was removed.
  • Formatting was changed.

...

The sequence listing should be comprehensive and include all of the necessary annotations so it should not provide details of the modified residue/s in the description only. The sequence listing should not rely on a reference to any external source of information, which includes a table in the description of the patent specification. 

As you note, WIPO ST.26 strongly recommends that the sequence should contain the unmodified nucleotide (or if not possible variable ‘n’) and a modified base feature. If there is a specific modified nucleotide which is not listed in Part 2 of Annex I of ST.26, then there should be both:

...